Research Paper Volume 15, Issue 11 pp 5052—5065

Regulation of endothelial ferroptosis by SESN1 in atherosclerosis and its related mechanism

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Figure 3. Overexpression of SESN1 inhibited ferroptosis in AS mice. (A) Immunofluorescence was used to detect the iron metabolism in vascular tissues. (B) The expressions of SESN1, P53, P21 and ferroptosis-related proteins were detected by western blot. ***P < 0.001 vs. Control; #P < 0.05, ###p < 0.001 vs. Ov-NC+Model.