Research Paper Volume 15, Issue 11 pp 5052—5065

Regulation of endothelial ferroptosis by SESN1 in atherosclerosis and its related mechanism

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Figure 2. Overexpression of SESN1 inhibited inflammation and oxidative stress in AS mice. (A) The results of HE staining. (B) ELISA was used to detect the levels of inflammatory factors in vascular tissues. (C) The kits were used to detect the expression of oxidative stress-related factors ROS, MDA and GSH. ***P < 0.001 vs. Control; ###p < 0.001 vs. Ov-NC+Model.