Research Paper Volume 15, Issue 11 pp 4949—4962

PZR promotes tumorigenicity of lung cancer cells by regulating cell migration and invasion via modulating oxidative stress and cell adhesion

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Figure 8. ROS inhibition by NAC reduced phosphorylation of multiple proteins involved in cell adhesion and migration. Vector-overexpressing (V-OE), and PZR-overexpressing (PZR-OE) SPC-A1 cells were treated with NAC (100 μM) for 1 h and then extracted in the RIPA buffer. Cells extract were subjected to Western blotting with the indicated antibodies.