Research Paper Volume 15, Issue 11 pp 4794—4819

Figure 7. Effects of inhibiting the expression of PVT1 in cell proliferation and migration in vitro. (A) The expression of PVT1 in normal and ESCA tissues. (B) KM survival analysis for ESCA patients with different PVT1 expressions; (C) The expression of PVT1 in HEEC and ESCA cells; (D) The transfection efficiency of PVT1-sh1#/sh2# in ECA-150 cell; (E) The transfection efficiency of PVT1-OE in KYSE-510 cell; (F, G) Knockdown of PVT1 inhibited ECA-150 cell proliferation and colony formation ability. (H, I) Overexpression of PVT1 promoted KYSE-510 cell proliferation and colony formation ability. Data are presented as mean ± SD. (*p < 0.05, **p < 0.01, ***p < 0.001).