Research Paper Volume 15, Issue 11 pp 4774—4793

Visfatin upregulates VEGF-C expression and lymphangiogenesis in esophageal cancer by activating MEK1/2-ERK and NF-κB signaling

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Figure 8. Schematic illustration of how signaling pathways participate in visfatin-induced stimulation of VEGF-C expression and the subsequent stimulation of ESCC lymphangiogenesis in esophageal cancer.