Research Paper Volume 15, Issue 11 pp 4746—4756

Calcium silicate-stimulated adipose-derived stem cells promote angiogenesis and improve skin wound healing

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Figure 5. CS-stimulated ADSCs enhance migration and angiogenic capacity of HUVEC. (AF) The HUVEC was treated with ADSCs, CS, or co-treated with ADSCs and CS. (A) The migration was measured by transwell assays in the cells. (B) The angiogenic capacity was analyzed by tube formation assays in the cell. (CF) The levels of VEGF, VEGFR2, bFGF, and bFGFR were assessed by qPCR in the cells. Data are presented as mean ± SD. Statistic significant differences were indicated: *P < 0.05, **P < 0.01.