Research Paper Volume 15, Issue 12 pp 5355—5380

Construction and experimental validation of a B cell-related gene signature to predict the prognosis and immunotherapeutic sensitivity in bladder cancer

class="figure-viewer-img"

Figure 5. The validation of the prognosis value of BCRS in BLCA. (A) The hazard ratios and the 95% confidence intervals of the variables in the predictive model. (B) A nomogram was drawn to visualize the predictive model. (CF) The distribution of the BCRSs and survival statuses of the BLCA cases from the TCGA-BLCA cohort (C), the GSE13507 cohort (D), the GSE31684 cohort (E), and the GSE32894 cohort (F). The cut-off values to divide all the subjects in these cohorts into low- and high-BCRS subgroup was equal to 2.75, which was detected by X-tile in the training cohort. (GJ) The Kaplan-Meier survival analyses of BCRS in the TCGA-BLCA cohort (G), the GSE13507 cohort (H), the GSE31684 cohort (I), and the GSE32894 cohort (J). (KN) The association between the survival statuses and BCRS stratification in the TCGA-BLCA cohort (K), the GSE13507 cohort (L), the GSE31684 cohort (M), and the GSE32894 cohort (N). BCRS, B cell-related score.