Research Paper Volume 15, Issue 10 pp 4122—4143
PCNT is a prognostic biomarker correlated with tumor immune microenvironment in hepatocellular carcinoma and promotes tumor progression by inhibiting cell cycle arrest
Figure 1. Expression and clinical role of PCNT mRNA in HCC. (A–C) PCNT mRNA levels in HCC and normal tissues in TCGA (A), GSE54236 (B), and GSE76427 (C) datasets. (D) PCNT mRNA levels in HCC tissues with lymph node metastasis. (E, F) PCNT mRNA gradually elevated with the tumor stage (E) and grades increased (F). (G, H) Higher PCNT mRNA levels correlated to poor OS (G) and disease-free survival (H). (I, J) Higher PCNT mRNA levels correlated to poor OS (I) and RFS (J) in stage I/II patients. (K, L) Higher PCNT mRNA levels correlated to poor OS (K) and RFS (L) in grade I/II patients.