Research Paper Volume 15, Issue 9 pp 3715—3737

Figure 4. Amyloid and phosphorylated (p)-tau burden analysis in the cortex and hippocampus of AD mice. Protein levels of amyloid precursor protein (APP), amyloid beta (Aβ) (A), p-tau (Tau^Thr181), and tau protein (B) in the cortex and hippocampus of AD mice, plasmin-activated water (PAW)-fed (AD+PAW) mice, and fecal microbiota transplantation (FMT) AD mice (AD+FMT) as measured by Western blotting. Statistical results (C) and (D) were analyzed from (A) and (B). Immunofluorescence analysis of Aβ (E) aggregation in the cortex (Cor) and hippocampus (Hip) of WT (a), AD (b), AD+PAW (c), and AD+FMT mice (d). Immunofluorescence analysis of p-tau (F) aggregation in the cortex (Cor) and hippocampus (Hip) of WT (a), AD (b), AD+PAW (c), and AD+FMT mice (d). Statistical results (G) and (H) were analyzed in the cortex and hippocampus from (E) and (F). All results were analyzed by ANOVA with a post hoc analysis. (^*p < 0.05, ^**p < 0.01, ^***p < 0.001). Mean values ± standard deviation of mean (SD) was shown.