Research Paper Volume 15, Issue 9 pp 3690—3714
MGME1 associates with poor prognosis and is vital for cell proliferation in lower-grade glioma
Figure 3. Correlation analysis of MGME1 in TCGA. (A) Association between MGME1 expression and clinical characteristics of LGG in TCGA. (B) Variance analysis of MGME1 expression and different clinical characteristics (including age, gender, grade, and 1p/19q, IDH, and MGMT statuses) in the TCGA dataset. (C) Prognostic analysis of high-MGME1 and low-MGME1 subtypes in the TCGA dataset. (D) Distribution of risk scores and OS of high-MGME1 and low-MGME1 subtypes in the TCGA dataset. (E) Distributions of OS of the two subtypes. (F) ROC curves representing the predictive value of the risk score in TCGA. (G, H) Univariate and multivariate Cox regression analyses of MGME1 expression and clinicopathological characteristics in TCGA. *P < 0.05, **P < 0.01, ***P < 0.001.