Research Paper Volume 15, Issue 9 pp 3465—3479

Figure 4. JDP2 inhibited the EMT of ARPE-19 cells. (A) The mRNA levels of E-cadherin and α-SMA in ARPE-19 cells transfected with empty vector or JDP2-expressing plasmid were determined via quantitative PCR. (B) Relative protein expression E-cadherin and α-SMA in ARPE-19 cells transfected with empty vector or JDP2-expressing plasmid (n = 3 for each group). (C) Migration of ARPE-19 cells after the overexpression of JDP2 or/and PA treatment (n = 3 for each group). (D) Expression of E-cadherin, Vimentin, Snail, α-SMA, Fibronectin, and JDP2 in ARPE-19 cells after the overexpression of JDP2 or/and PA treatment (n = 3 for each group). ^*P < 0.05, ^**P < 0.01, and ^***P < 0.001, as compared with the indicated controls.