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Figure 2
Figure 2.PA enhanced the effect of miR-143-5p in promoting the EMT of ARPE-19 cells. (A) miR-143-5p expression in ARPE-19 cells was determined via quantitative PCR; n = 3 for each group. (B) Protein expression of E-cadherin, Fibronectin, α-SMA, Snail, and Vimentin protein levels in ARPE-19 cells transfected with NC or miR-143-5p mimics (n = 3 for each group). (C) Protein expression of E-cadherin, Fibronectin, α-SMA, Snail, and Vimentin in ARPE-19 cells transfected with NC or miR-143-5p inhibitors (n = 3 for each group). (D) Migration of ARPE-19 cells after the overexpression of miR-143-5p inhibitors or/and PA treatment (n = 3 for each group). (E) Expression of E-cadherin, Fibronectin, α-SMA, Snail, and Vimentin in ARPE-19 cells after the overexpression of miR-143-5p inhibitors or/and PA treatment (n = 3 for each group). *P < 0.05, **P < 0.01, and ***P < 0.001, as compared with the indicated group.
Figure 2 — Palmitic acid–induced microRNA-143-5p expression promotes the epithelial–mesenchymal transition of retinal pigment epithelium via negatively regulating JDP2 | Aging