Research Paper Volume 15, Issue 9 pp 3442—3464
Identification and validation of immunogenic cell death-related score in uveal melanoma to improve prediction of prognosis and response to immunotherapy
Figure 1. Clustering of uveal melanoma patients based on ICD-related genes. (A, B) The cophenetic coefficient map (A) and heatmap (B) of NMF clustering results of UVM patients from the TCGA-UVM cohort. (C) Kaplan-Meier curves of OS in the C1 and C2 clusters of UVM patients from the TCGA-UVM cohort. (D, E) The cophenetic coefficient map (D) and heatmap (E) of NMF clustering results of UVM patients from the GSE22138 cohort. (F) Kaplan-Meier curves of OS in the C1 and C2 clusters of UVM patients from the GSE22138 cohort. (G) PCA analysis of the C1 and C2 cluster of UVM patients from the TCGA-UVM cohort. (H, I) Kaplan-Meier curves of DSS (H) and PFI (I) in the C1 and C2 clusters of UVM patients from the TCGA-UVM cohort. (J) The expression levels of the ICD-related genes in C1 and C2 clusters of UVM patients from the TCGA-UVM cohort. Abbreviation: Ns: not significant. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.