Research Paper Volume 15, Issue 9 pp 3249—3272

Figure 4. Indirect effects in the associations of the minor alleles of four SNPs from the MLXIPL gene with AD through lipids in two samples drawn from US cohorts (A) and UK biobank (B). The Y-axis shows the indirect effect sizes beta of the associations of respective SNPs with AD through the mediators depicted on the X axis. The X-axis shows the mediator variable used in the model. The vertical solid lines indicate 95% confidence intervals (CIs). Asterisks indicate different levels of significance, i.e., ^*5 × 10⁻⁴ ≤ p < 0.05; ^**5 × 10⁻⁶ ≤ p < 5 × 10⁻⁴.