Research Paper Volume 15, Issue 8 pp 3035—3051
TYRO3 promotes tumorigenesis and drug resistance in colorectal cancer by enhancing the epithelial-mesenchymal transition process
Figure 5. The proliferation and migration ability in drug-resistant cells were inhibited by down-regulating TYRO3 expression. (A) Proliferation ability of H-DR and T-DR transfected with TYRO3-shRNA assessed by CCK-8 assay. (B) Colony formation capacity of H-DR and T-DR transfected with TYRO3-shRNA assessed. (C) Colony formation units counted. (D) Migration capacity of H-DR and T-DR transfected with TYRO3-shRNA assessed. (E) Migration cell numbers counted. Abbreviations: NC: negative control; KD: TYRO3-shRNA. *P < 0.05, **P < 0.01, ***P < 0.001.