Research Paper Volume 15, Issue 7 pp 2667—2688

Machine learning-based construction of immunogenic cell death-related score for improving prognosis and response to immunotherapy in melanoma

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Figure 7. Comparison between ICDscore and other forms of cell death-based signatures. (AD) The performance of ICDscore was compared with other forms of cell death-based signatures in predicting prognosis in the GSE65904 (A), TCGA-SKCM (B), GSE54467 (C), and GSE22153 (D) datasets. Statistic tests: two-sided z-score test. Data were presented as mean ± 95% confidence interval [CI]. (EI) The performance of ICDscore was compared with other forms of cell death-based signatures in predicting immunotherapy efficiency in GSE35640 (E), VanAllen15 (F), PUCH (G), Liu19 (H), and Gide19 (I) cohorts. Ns, not significant; *p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001.