Research Paper Volume 15, Issue 7 pp 2582—2609

Figure 11. AIF-1 promotes RCC cell proliferation and invasion. (A) The protein expression levels of AIF-1 in 786-O cells after transfection with shAIF-1 or shNC. (B) CCK-8 assay showing proliferation of cells following knockdown of AIF-1. (C and D) Representative images and quantification of colony formation assays of 786-O cells transfected with shAIF-1. (E and F) Representative images and quantification of EdU assays of 786-O cells transfected with shAIF-1. Scale bar, 50 μm. (G and H) Transwell assays showed the suppressed migration and invasion ability of 786-O cells transfected with shAIF-1. (^*P < 0.05, ^**P < 0.01, and ^***P < 0.001).