Research Paper Volume 15, Issue 9 pp 3230—3248

Increased expression of musashi 1 on breast cancer cells has implication to understand dormancy and survival in bone marrow

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Figure 2. CSCs in Msi-1 knockdown BCCs. MDA-MB-231 with stable pOct4a-GFP was knockdown for Msi 1 (A) and then analyzed for Oct4ahi cells (B). The mean±SD percentages of Oct4ahi cells in the knockdown and vector (with scramble shRNA) transfected BCCs are presented for four different experiments (C). * p<0.05 vs. vector alone. The mean±SD percentages of tumorspheres for the Msi 1 knockdown and vector controls are presented for three different experiments (D). * p<0.05 vs. Msi 1 shRNA.