Figure 6.DMC-BH inhibits the growth of xenografts derived from HCT116 and HT-29 cells. (A) Volumes of xenografts derived from CRC cells treated with 20 mg/kg DMC-BH or curcumin. (B) Xenograft weights of CRC cells treated with 20 mg/kg DMC-BH or curcumin. (C) Immunohistochemical analysis of p-AKT and p-mTOR expression in xenografts.
(D) Western blot analysis of p-AKT and p-mTOR expression in xenografts. (E) Western blot analysis of MMP-2 and MMP-9 in xenografts.
