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Research Paper Volume 15, Issue 6 pp 2097—2114
ADAMTS1 induces epithelial-mesenchymal transition pathway in non-small cell lung cancer by regulating TGF-β
Figure 8. Effects of ADAMTS1 and KTFR on proliferation, cycle, migration, invasion, and EMT of the NSCLC A549 and H226 cell line. (A) The wound-healing assay showed the migration of A549 cells after treatment with KTFR. (B) Protein expressions of E-cadherin, N-cadherin, and Vimentin in A549 cells were detected using Western blot. (C) Transwell assay was used to detect migration and invasion of A549 cells (scale bar=50 μm). (D) The wound-healing assay showed the migration of H226 cells after adding KTFR. (E) Protein expressions of E-cadherin, N-cadherin, and vimentin in H226 cells were detected using Western blot. (F) Transwell assays were used to detect migration and invasion of H226 cells (scale bar=50 μm). NS P>0.05, **P<0.01, ***P<0.001. N=3.