Expression of Concern
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 15, Issue 10 pp 4071—4083
lncRNA PITPNA-AS1 promotes cell proliferation and metastasis in hepatocellular carcinoma by upregulating PDGFD
Figure 4. PDGFD is a downstream target of miR-363-3p. (A) A binding motif of PDGFD within miR-363-3p predicted byStarBase3.0 (http://starbase.sysu.edu.cn/). (B) Luciferase activity in Huh7 and Hep3B cells transfected with miR-NC or miR-363-5p mimic. (C) PDGFD levels in Huh7 and Hep3B cells treated with NC-inhibitor or miR-363-5p inhibitor. (D) Relative expression of miR-363-5p in Huh7 and Hep3B cells treated with NC-inhibitor or miR-363-5p inhibitor. (E) PDGFD expression levels in Huh7 and Hep3B cells transfected with sh-NC, sh-PITPNA-AS1#1, or sh-PITPNA-AS1#1+miR-363-5p inhibitor were quantified by qRT-PCR and western blot. **P < 0.01, compared to the sh-NC group; ^^P < 0.01, compared to the sh-PITPNA-AS1#1 group.