Research Paper Volume 15, Issue 8 pp 2920—2936
ESM1 promotes angiogenesis in colorectal cancer by activating PI3K/Akt/mTOR pathway, thus accelerating tumor progression
Figure 7. Activated/phosphorylated protein levels of the PI3K/Akt/mTOR signaling pathway in each group. (A, B) Phosphorylated and total protein levels of PI3K, Akt and mTOR in ESM1-NC group, ESM1-mimic group, ESM1-NC + PI3K inhibitor group and ESM1-mimic + PI3K inhibitor group. (C, D) Statistics for phosphorylated and total protein levels of PI3K, Akt and mTOR. *p < 0.05 and **p < 0.01 vs. ESM1-NC group.