Review Volume 15, Issue 4 pp 905—913

Cellular senescence: when growth stimulation meets cell cycle arrest

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Figure 1. Geroconversion as a form of growth. (A) Proliferating cells. Cellular enlargement (growth) is followed by cell division. mTOR is shown as one of the drivers of growth. (B) Arrested cells. In the arrest cell (p21 and p16) cellular enlargement is followed by cell division. mTOR is shown as one of the drivers of geroconversion.