Research Paper Volume 15, Issue 5 pp 1343—1357

Figure 8. THBS2 and VCAN expression in gastric cancer and gastritis by immunohistochemistry. THBS2 protein was mainly expressed at the cytoplasm. The expression of THBS2 protein in gastric cancer was significantly higher than that in gastritis (P = 0.003). (A) Positive expression of THBS2 protein in gastric cancer; (B) Negative expression of THBS2 protein in gastric cancer; (C) Positive expression of THBS2 protein in gastritis; (D) Negative expression of THBS2 protein in gastritis. VCAN protein expressed mainly at the cytoplasm and cell membrane. The expression of VCAN protein in gastric cancer was significantly higher than that in gastritis (P < 0.001). (E) Positive expression of VCAN protein in gastric cancer; (F) Negative expression of VCAN protein in gastric cancer; (G) Positive expression of VCAN protein in gastritis; (H) Negative expression of VCAN protein in gastritis.