Research Paper Volume 15, Issue 1 pp 37—52

Figure 3. RORα was induced in CNV and regulated VEGFR2 and TNFα levels in laser-induced CNV. (A, B) Western blotting images (A) and densitometric analysis (B) of protein levels of RORα from choroid/RPE complexes with laser-induced CNV from C57BL/6J mice at 1, 3, 5 and 7 days (d) post-laser, compared with β-actin. β-actin served as loading control. Each band represents pooled sample from 3 retinas. n = 3 mice/group. (C, D) Western blotting images (C) and densitometric analysis (D) showing TNFα and VEGFR2 protein levels in choroid/RPE complexes at 3, 5, and 7 days after laser-induced CNV in Rora^sg/sg and WT eyes, compared with β-actin as loading control. Each band represents pooled sample from 3 retinas. n = 3 mice/group. ^*P ≤ 0.05; ^**P ≤ 0.01; ^***P ≤ 0.001; ^****P ≤ 0.0001.