Research Paper Volume 15, Issue 1 pp 261—275

Figure 3. Luteolin could regulate the expressions of Sirt1, Nlrp3, AC-NF -κB, NF-κB, Nlrp3, GSDMD-N and GSDMD proteins in hippocampi and tears of mice. (A–F) Western Blot was used to detect the effects of luteolin on protein bands of Sirt1, Nlrp3, AC-NF-κB, NF-κB, GSDMD-N and GSDMD in the hippocampus of mice. (G–L) Western Blot analysis of the effects of luteolin on protein bands of Sirt1, Nlrp3, AC-NF -κB, NF-κB, GSDMD-N and GSDMD in mice cornea. (M) Molecular docking of sitrt1 and luteolin in discovery studio. (N) Molecular docking of sirt1 and Resveratrol by discovery studio. Data were analyzed by mean ± scanning electron microscopy. Compared with blank group, ^##P < 0.01; Comparison with model group ^*P < 0.05, ^**P < 0.01, n = 9.