Research Paper Volume 15, Issue 1 pp 179—192
lncRNA HCG11 suppresses cell proliferation in hormone receptor-positive breast cancer via SRSF1/β-catenin
Figure 7. Overexpression of SRSF1 eliminated the antitumor effect of HCG11 on HR-positive BC cells. (A, B) SRSF1 rescued the suppressive effects of HCG11 on MCF-7 and BT-474 cell proliferation by CCK8 assay. (C, D) SRSF1 rescued the suppressive effects of HCG11 on MCF-7 and BT-474 cell line proliferation by colony formation assay. (E) SRSF1 rescued the low expression of β-catenin protein level caused by HCG11 by Western blot. **p<0.01, ***p<0.001, **** p<0.0001.