Research Paper Volume 15, Issue 1 pp 179—192

lncRNA HCG11 suppresses cell proliferation in hormone receptor-positive breast cancer via SRSF1/β-catenin

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Figure 3. HCG11 could bind to SRSF1. (A) Anti-SRSF1 RIP assay was applied to validate the binding of SRSF1 to HCG11. (B) Full-length and truncated SRSF1 plasmid with FLAG-tagged vectors were constructed. (C) Anti-Flag RIP assay was applied to validate the binding of SRSF1 to HCG11. (D, E) Protein level of SRSF1 in MCF-7 and BT-474 cell line transfected with SI-HCG11. **p<0.01, ***p<0.001, **** p<0.0001.