Research Paper Volume 15, Issue 1 pp 92—107
Comprehensive bioinformatics analysis reveals the significance of forkhead box family members in pancreatic adenocarcinoma
Figure 3. Genetic alterations and promoter methylation levels of the 15 differentially expressed FOXs in PAAD patients. (A) Summary of genetic alterations of different expressed FOXs in PAAD. All FOXs were altered in 19 samples of 175 patients with PAAD, accounting for 11% of the queried patients/samples. (B) Results from UALCAN showed downregulation of the promoter methylation level of FOXD1, FOXJ1, and FOXK1 in tumor tissues. (C) The methylation levels of FOXC2, FOXF1, FOXF2, FOXM1, and FOXN3 were upregulated in tumor tissues.