Research Paper Volume 14, Issue 24 pp 10081—10092

SALL4 activates PI3K/AKT signaling pathway through targeting PTEN, thus facilitating migration, invasion and proliferation of hepatocellular carcinoma cells

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Figure 7. SALL4 increased the tumor progression in nude mice. (A) SMMC 7721 cells transfected with SALL4 mimic-NC, mimic, SALL4 inhibitor-NC and inhibitor were subcutaneous injected in nude mice; (B) Statistical data for tumor weight and volume. *p < 0.05, **p < 0.01 vs. NC group.