Research Paper Volume 14, Issue 24 pp 10081—10092
SALL4 activates PI3K/AKT signaling pathway through targeting PTEN, thus facilitating migration, invasion and proliferation of hepatocellular carcinoma cells
Figure 4. The effects of SALL4 on the migrated capacity of hepatic cancers. Distances of cell migration in HepG2 (A) and SMMC-7721 (B) HCC cells at 0 h, 24 hs and 48 hs after scratch, and the higher expression of SALL4 (mimic) decreased the scratch distance and the inhibited expression of SALL4 (inhibitor) increased the scratch distance after 24 and 48 hs. n = 3/group, t test between two groups, and by one-way analysis of variance among groups. *p < 0.05, **p < 0.01 vs. NC group.