Figure 3 — SALL4 activates PI3K/AKT signaling pathway through targeting PTEN, thus facilitating migration, invasion and proliferation of hepatocellular carcinoma cells

Research Paper|Volume 14, Issue 24|pp. 10081–10092

SALL4 activates PI3K/AKT signaling pathway through targeting PTEN, thus facilitating migration, invasion and proliferation of hepatocellular carcinoma cells

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Figure 3.The effects of SALL4 on the proliferation of hepatic cancers tested by flow cytometry. SALL4 mimic inhibited the cellular ratio in G1 stage and increased the cellular ratio of S stage in both HepG2 (A) and SMMC-7721 cells (B); SALL4 inhibitor suppressed the ratio of G1 stage and increased the ratio of S stage in both HepG2 (A) and SMMC-7721 cells. n = 3/group, t test between two groups, and by one-way analysis of variance among groups. ^*p < 0.05, ^**p < 0.01 vs. NC group.