Research Paper Volume 14, Issue 24 pp 10081—10092
SALL4 activates PI3K/AKT signaling pathway through targeting PTEN, thus facilitating migration, invasion and proliferation of hepatocellular carcinoma cells
Figure 2. The roles of SALL4 on the proliferation of hepatoma tested by CCK8 assay. SALL4 mimic increased the OD value in both HepG2 (A) and SMMC-7721 cells (B); and SALL4 inhibited the OD value in both HepG2 (A) and SMMC-7721 cells (B) n = 3/group, t test between two groups, and by one-way analysis of variance among groups. *p < 0.05, **p < 0.01 mimic vs. mimic NC group, #p < 0.05, ##p < 0.01 inhibitor vs. inhibitor NC group.