Research Paper Volume 14, Issue 23 pp 9679—9698
SKA1 promotes tumor metastasis via SAFB-mediated transcription repression of DUSP6 in clear cell renal cell carcinoma
Figure 6. DUSP6 mediates SKA1 depletion-induced tumor suppression. (A and B), Transwell assay was used to assess the invasiveness and migration of cells transfected with indicated constructs. Data shown are mean from three independent experiments performed in triplicate. *P < 0.05. (C) Western blot analysis of E-cadherin and vimentin protein levels in cells transfected with indicated constructs after TGF-β1 treatment. One representative experiment of three independent experiments are shown.