Figure 1.High SKA1 expression positively correlates with human renal cancer progression. (A–C), Analysis of SKA1 mRNA expression in ccRCC samples from TCGA-KIRC. (A) Analysis on SKA1 mRNA levels among ccRCC tissues, paired normal tissues, and metastatic tumor tissues (N = 72). (B) Analysis on SKA1 mRNA levels in low Fuhrman grade (G1+G2) and advanced-grade (G3+G4). (C) Kaplan–Meier analysis of ccRCC patient survival. (D) Analysis on SKA1 mRNA levels among ccRCC tissues, paired normal tissues, and metastatic tumor tissues (N = 83). (E) Representative images of IHC staining (magnification, ×100) for SKA1 protein from 83 ccRCC specimens.
