Research Paper

Adipocyte-derived exosomal miR-30c-5p promotes ovarian angiogenesis in polycystic ovary syndrome via the SOCS3/STAT3/VEGFA pathway

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Figure 9. Schematic illustration of adipocyte-derived exosomal miR-30c-5p activating the STAT3/VEGFA pathway by targeting SOCS3 in HOMECs. Exosomes derived from adipocytes promote the activation of the STAT3/VEGFA pathway in HOMECs by transporting miR-30c-5p to directly inhibit SOCS3 expression at the post-transcriptional level.