Research Paper
Adipocyte-derived exosomal miR-30c-5p promotes ovarian angiogenesis in polycystic ovary syndrome via the SOCS3/STAT3/VEGFA pathway
Figure 8. Adipocyte-derived exosomal miR-30c-5p mediates ovarian angiogenesis through the SOCS3/STAT3/VEGFA pathway. (A) Visualization of the ovarian morphology in the indicated groups by HE staining. (B) Detection of SOCS3, CD31 and VEGFA expression in the ovaries in the indicated groups by IHC staining. (C) Western blotting analyses of the SOCS3/STAT3/VEGFA pathway expression in the indicated groups. Primary follicles (PFs), granulosa cells (GCs), theca cells (TCs), secondary follicles (SFs), antral follicles (AFs), corpus luteum (CL), and cystic follicles (CFs). Data are presented as mean ± SD for three independent experiments. *P<0.05, ** P<0.01, ***P<0.001.