Figure 4. SOCS3 is a target gene of miR-30c-5p. (A, B) Bioinformatic analyses of target genes of miR-30c-5p. (C) Prediction of the binding site of miR-30c-5p in the 3’-UTR of SOCS3 mRNA by TargetScan. (D) Confirmation of the targeting relationship between miR-30c-5p and SOCS3 by the dual luciferase reporter assay. Data are presented as mean ± SD for three independent experiments. ***P<0.001.