Research Paper Volume 14, Issue 24 pp 9890—9907

Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF

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Figure 5. Cellular uptake of exosomes and cell transfection efficiency. (A) Sevoflurane-induced POCD-derived exosomes were labeled by PKH67 (green), and cytoskeleton of HMC3 cells was stained by Actin (red). Exosomes could be taken up by HMC3 cells after co-cultured. (B) The level of miR-584-5p after transfected with negative control (NC) mimics and miR-584-5p mimics. *: P < 0.05, compared with the control group.