Figure 6. Senescent cell elimination drug BPTES improves the skin senescence phenotype of transplanted aged human skin. (A) Evaluation of skin collagen deposition using representative images of MT and H&E staining. (B) Quantification of collagen density in skin sections from the indicated mice. Data represent three or more random sites in each section (n = 3–5). (C) Relative mRNA levels of Col1a1 in the skin from aged mice. *p < 0.05, Mann–Whitney U test; bar = 100 μm.