Research Paper Volume 15, Issue 2 pp 308—352

Figure 1. Body weight, bone marrow adipose tissue, and heart weight during aging. The low body weight, LBW, and high body weight, HBW, groups showed differences in bone marrow adipose tissue. 6 mo endurance exercise increased heart weight in the HBW subgroup. (A) The body weight of 18 mo. ^*: p < 0.05 and ^***: p < 0.001, CTRL/HBW vs. CTRL/LBW mice (red asterisks). ^*: p < 0.05 and ^***: p < 0.001, VWR/HBW vs. VWR/LBW mice (blue asterisks). ^#: p < 0.05, VWR/HBW vs. CTRL/HBW mice. (B and C) Bone marrow adipose tissue/total area (BMAT/TA) ratio in 18 mo. ^**: p < 0.01, CTRL/HBW vs. CTRL/LBW mice. (D) Heart muscle weight/body weight (HW/BW) ratio in 18 mo. ^*: p < 0.05, CTRL/HBW vs. VWR/HBW mice. (E) The body weight of 22 mo. ^*: p < 0.05, ^**: p < 0.01, and ^***: p < 0.001, CTRL/HBW vs. CTRL/LBW mice. ^#: p < 0.05, VWR/HBW vs. CTRL/HBW mice. (F and G) Bone marrow adipose tissue/total area (BMAT/TA) ratio in 22 mo. (H) Heart muscle weight/body weight (HW/BW) ratio in 22 mo (D). Abbreviations: CTRL: control group; VWR: voluntary wheel running group; CBW: Combined groups; LBW: Low body weight group; HBW: High body weight group.