Research Paper Volume 14, Issue 22 pp 9020—9036
Molecular subtypes identified by pyroptosis-related genes are associated with tumor microenvironment cell infiltration in colon cancer
Figure 3. TME cell infiltration patterns in distinct pyroptosis characterizations. (A) The abundance of 28 TME cell infiltration among three pyroptosis characterization clusters visualized by heatmap. (B) Differences of 28 TME cell infiltration abundance between three pyroptosis characterization clusters. (C, D) GSVA enrichment showing the activation states of biological pathways in distinct clusters. (C) cluster 1 vs cluster 3; (D) cluster 2 vs cluster 3. (E) Difference in the immune-activation related gene expression among three clusters. (F) Difference in the TGFβ-EMT pathway-related gene expression among three pyroptosis characterization clusters. (G) Difference in the immune-checkpoint related gene expression among three clusters.