Figure 3. DSC2 inhibits the ERK1/2 signaling pathway. The expression levels of ERK1/2, p-ERK1/2, and c-MYC in overExp-DSC2-transfected LM3 and shRNA-DSC2-1-transfected 7721 cells were determined by Western blot analysis (repeated three times). *P < 0.05, **P < 0.01, ***P < 0.001.