Research Paper Volume 14, Issue 20 pp 8498—8567

Figure 4. Kaplan-Meier (KM) analysis of cadherin (CDH) family genes in the distant metastasis-free survival (DMFS) of breast cancer patients. The hazard ratio (HR) represents a prognostic value of breast cancer patients. Log[rank p] was utilized to find out the level of prognostic significance of breast cancer patients. In addition, log[rank p] of <0.05 was considered a significant difference in the prognosis of breast cancer patients. High expressions of CDH1/2/3/4/5/7/9/10/11/12/13/15/16/19/26 were significant compared to low expressions, which are highlighted with p values in red boxes. The HRs of CDH1/2/3/4/7/9/10/11/12/13/15/16/26 were significantly higher, which are marked in yellow boxes, indicating poor prognostic outcomes in breast cancer. In contrast, the HRs of CDH5/19 were significantly lower, which were marked in blue boxes, indicating better prognostic outcomes in breast cancer.