Research Paper Volume 14, Issue 20 pp 8205—8220

Age-associated changes in microglia activation and Sirtuin-1- chromatin binding patterns

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Figure 3. BBB integrity via detection of fibrinogen in PFC from young and elder animals. Paraffin-embedded PFC sections were stained with antibody anti- fibrinogen. (A) representative image from young (4-7 yo) group, (B) representative image from the shorter-lived group, (C) representative image from longer-lived animals. All images are 20X magnification.