Research Paper Volume 14, Issue 19 pp 7959—7971

Figure 1. APEX1 is a novel HCC-related oncogene. (A) The expression of APEX1 was evaluated by immunohistochemistry analysis of HCC specimens and matched adjacent normal tissues (n = 80 cases). (B) Bioinformatics analysis using the UALCAN tool on TCGA dataset compared the mRNA expression of APEX1 in HCC (n = 371) and normal (n = 50) tissues (Left). The expression of APEX1 was also analyzed in HCC tissues at various stages (Right). (C) APEX1 protein expression was evaluated in HCC cells and normal hepatic cells by a Western blot assay. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001.