Figure 1. Dynamic RNA modifications. Multiple internal modifications within mRNAs, and specific groups of modifications are highlighted, along with modification deposition, removal, and base pairing of modification pairs for downstream recognition. m6A, N6-adenosine methylation; m5C, 5-methylcytidin; ac4C, N4-acetylcytidine; Ψ, pseudouridine; A-to-I, adenosine-to-inosine; m7G, N7-methylguanosine; m1A, N1-adenosine methylation.