Figure 5. GSEA used to validate the gene signatures, including negative regulation of (A) CELL_CYCLE, (B) DNA_REPLICATION, (C) P53_SIGNALING_PATHWAY, (D) HOMOLOGOUS_RECOMBINATION, (E) MISMATCH_REPAIR, (F) OOCYTE_MEIOSIS, (G) PROGESTERONE_MEDIATED_OOCYTE_MATURATION, (H) CYTOSOLIC_DNA_SENSING_PATHWAY, (I) PRIMARY_IMMUNODEFICIENCY, (J) NATURAL_KILLER_CELL MEDIATED_CYTOTOXICITY, (K) FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS, (L) CYTOKINE _CYTOKINE_RECEPTOR_INTERACTION.