Research Paper Volume 14, Issue 17 pp 7026—7037

Clinical significance and potential mechanism of heat shock factor 1 in acute myeloid leukemia

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Figure 1. The expression level, diagnostic efficacy and prognostic significance of HSF family in acute myeloid leukemia (AML) based on data from the cancer genome atlas (TCGA) and the genotype–tissue expression (GETx) processed using the TOIL pipeline. The validation datasets were downloaded from the Gene Expression Omnibus (GEO), and Cancer Cell Line Encyclopedia (CCLE). (AC) The expression level, diagnostic efficacy and prognostic significance of HSF1 in AML. (DF) The expression level, diagnostic efficacy and prognostic significance of HSF2 in AML. (GI) The expression level, diagnostic efficacy and prognostic significance of HSF4 in AML. (JL) The expression level, diagnostic efficacy and prognostic significance of HSF5 in AML. (M) The expression level of HSFs examined in leukemia cell lines. ****P < 0.001.