Figure 4. The COL1A2 promoter methylation level in colon adenocarcinoma based on various clinicopathological parameters. (A) Age. (B) Gender. (C) Weight. Normal weight: 18.5 ≤ BMI < 25; Overweight: 25 ≤ BMI < 30; Obese: 30 ≤ BMI<40; Extreme obese: BMI > 40. Abbreviation: BMI: body-mass-index. (D) Histological subtypes. (E) Cancer stage. (F) Nodal metastasis status. #P < 0.05; ##P < 0.01; ###P < 0.001.